The effect of diatrizoate salts on vasopressin-induced volume flow across the excised toad urinary bladder.
نویسندگان
چکیده
منابع مشابه
Relationship of aggregated intramembranous particles to water permeability in vasopressin-treated toad urinary bladder.
It has been previously demonstrated with freeze-fracture electron microscopy that vasopressin induces specific structural alterations of the luminal membrane of granular cells from toad urinary bladder in a dose-dependent fashion. These alterations consist of aggregated intramembranous particles and are observed both in the presence and absence of an osmotic gradient. We examined the effect of ...
متن کاملSelective inhibition of osmotic water flow by general anesthetics to toad urinary bladder.
Vasopressin increases the permeability of the total urinary bladder, an analogue of the mammalian renal collecting duct, to water and small solutes, especially the amide urea. We have observed that three general anesthetic agents of clinical importance, the gases methoxyflurane and halothane and the ultrashortacting barbiturate methohexital, reversibly inhibit vasopressin-stimulated water flow,...
متن کامل45Ca fluxes in isolated toad bladder epithelial cells: effects of agents which alter water or sodium transport.
Vasopressin enhances osmotic water flow and sodium transport across the toad urinary bladder by mechanisms involving cyclic AMP and calcium. It is believed that changes in intracellular calcium concentration or in its binding to membranes may in part mediate the effects of vasopressin. In addition, several agents which alter the response of the toad bladder to vasopressin may also act by alteri...
متن کاملEffect of phloretin on water and solute movement in the toad bladder.
It is generally believed that urea crosses the cell membrane through aqueous channels, and that its movement across the membrane is accelerated in the direction of net water flow (solvent drag effect). The present report presents evidence for a vasopressin-sensitive pathway for the movement of urea, other amides, and certain non-amides, which is independent of water flow. Phloretin, when presen...
متن کاملVery high water permeability in vasopressin-induced endocytic vesicles from toad urinary bladder
The regulation of transepithelial water permeability in toad urinary bladder is believed to involve a cycling of endocytic vesicles containing water transporters between an intracellular compartment and the cell luminal membrane. Endocytic vesicles arising from luminal membrane were labeled selectively in the intact toad bladder with the impermeant fluid-phase markers 6-carboxyfluorescein (6CF)...
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عنوان ژورنال:
- The Journal of pharmacology and experimental therapeutics
دوره 204 2 شماره
صفحات -
تاریخ انتشار 1978